What are GLP-1s and why are they controversial

What Are Semaglutides?

Semaglutides are a GLP-1 which stands for glucagon-like peptide-1, a natural hormone your body makes. It helps regulate blood sugar, appetite, and digestion.


Semaglutide medications (such as Ozempic, Wegovy or Mounjaro) copy this hormone.

They:

Slow down how quickly food leaves your stomach (so you feel full for longer).

Reduce appetite and cravings.

Help balance blood sugar levels.


They were originally developed to treat type 2 diabetes, but more recently have been used

to support weight management.


Why Are They Controversial?

Semaglutides have become very popular, and that raises some debates:


Access and fairness – They’re sometimes in short supply, which can affect people with diabetes who need them.

Long-term effects – While short-term results are clear, research on the long-term impact is still developing.

Quick-fix perception – Some people see them as an “easy way out” for weight loss, which can overshadow the importance of lifestyle, nutrition, and underlying health.

Cost – These medicines can be expensive and not always available on the NHS

except for specific health conditions.


Possible Side Effects

Not everyone gets them, but some of the more common side effects include:

● Nausea and vomiting

● Constipation or diarrhoea

● Bloating or indigestion

● Reduced appetite (which is part of how they work, but can sometimes lead to too

little food intake)


Less common but more serious risks can include:

Gallstones or gallbladder problems

Pancreatitis (inflammation of the pancreas)

Nutrient deficiencies if someone consistently eats too little


The Bottom Line

Semaglutide medications can be powerful tools for managing diabetes and weight, but they’re not suitable for everyone and not without risks. They work best alongside healthy eating, regular movement, good sleep, and stress management—rather than replacing them.


If you are considering taking medication such as Ozempic, Mounjaro or Wegovy, or perhaps

you are already on one, contact me to get nutritional support to minimise side effects and

make sure that weight stays off for good!

The Oxford Clinic for Nutrition

24 Barley Close, WallingfordUnited Kingdom

by Megan Oliver 24 September 2025
Fasting for Women and Why it’s controversial Of all the subjects I discuss, fasting is by far one of the most divisive. Yet it’s also one I feel strongly about—because the evidence is clear, and I want to help women avoid the many traps it sets. Whilst some women report feeling well when fasting, the longer-term research paints a very different picture. Why is that? Women Are Not Small Men For far too long, women have been following health and fitness advice based on male physiology. Whether it’s training, weight management, or even medical treatment, most of the recommendations stem from studies carried out on men. Fasting is no exception. Some studies suggest benefits for active men , yet the data shows fasting often has the reverse effect for active women . Research is conclusive: there are sex- specific differences in energy metabolism and metabolic balance. Women, compared with men, are more efficient at conserving fat and protein (for fuel, rather than to protect lean tissue) during times of food shortage or prolonged exertion. ( A quick note : I’m talking here about active women—those who exercise with purpose. In sedentary populations, fasting may offer some benefits. But for active women, it tends to cause more harm than good.) The Role of the Hypothalamus So why does fasting affect women more negatively than men? Neuropeptides play a crucial role in reproductive health , hormone regulation , blood sugar control, appetite , and body composition . Here’s the key point —those that stimulate appetite, such as Neuropeptide Y, are naturally lower in women at rest and in non-stressful situations, but they rise more sharply in response to food restriction than they do in men. When the brain senses a drop in nutrients—especially carbohydrates—neuropeptide production shifts, driving the body to conserve energy more aggressively. Add the stress of exercise, and further hormonal changes occur. In the short term, women experience a stronger physiological drive to eat. Over time, if energy needs remain unmet, thyroid function can decline, menstrual cycles may become irregular, and increases in body fat are often observed. Sound familiar? This is why women who fast alongside male partners or friends often feel disheartened: he gets leaner, trains well, and feels mentally sharp—while she gains weight, feels anxious, and struggles with energy and performance.
by Megan Oliver 23 September 2025
As the days shorten and temperatures drop , it’s very common to notice a stronger appetite and more cravings for hearty, comforting foods . This isn’t just in your head — there are real biological and psychological reasons behind it.
7 February 2025
Magnesium is a go-to trendy supplement at the moment, but why is that and should you be including more in your diet?
17 December 2024
You probably already know that stress is not a good thing for your body and soul. Perhaps you have even had suggested to you that you should work on a stress action plan to reduce it. In theory, destressing should be as simple as breathing out, but in practice – and especially when life gets hectic - it often feels like another task on an endless to-do list. The key is in making it simple and enjoyable. Here are 7 lovely ideas you can weave into your daily routine. And the best part? They're all activities you'll genuinely want to indulge in.
14 October 2024
Did you see this Panorama programme? Chances are, even if you haven't watched it yet, you have heard about it. As soon as it came out I had clients asking me what I thought and saying it had frightened them. So, for what it's worth, here is my opinion on it... The menopause industry (and the health industry in general) is booming and there are so many new products, "influencers" and celebrities making promises that are just not backed by any decent research. It's massively confusing and my clients often say they are totally bamboozled, not knowing where to start. There is still such a stigma regarding HRT (a hangover from the infamous Women's Health Initiative study), that women often seek out a "natural" solution before heading down the path of hormone therapy, and an industry has been built capitalising on this. My advice would be that anyone offering you a wonder drug or quick fix, should be treated with the utmost caution! You won't be surprised when I say that I believe that diet and lifestyle modifications can make a massive difference to your menopause experience. I see it all the time with my clients, who regain their energy and feel more like themselves by making changes. Yes, I do recommend supplements to clients, but there is no one-size fits all and they should be used with caution. I always cross check any interactions with any medications and health conditions, because they can have a powerful effect. As to the programme's negative views on Dr Newson, I cannot talk about HRT levels as that is outside my scope of practice but I would suggest that she has done more to positively promote women's health than many others. The industry is thriving in part because the NHS is failing to help and voices, especially qualified medical ones like Dr Newson, are helping drive much needed change.
22 July 2024
I love the summer holidays, but the chance to break free from the normal routine of frantic dashes between the school gates and work brings with it lots of challenges. Many of my clients go into a bit of a panic as their big summer holiday approaches, rather like they do at Christmas. When it comes to healthy eating, the strategies for coping with both – and for that I mean not undoing all your previous good work – are very similar. The key is to have a plan and to be really clear on what matters to you most. Here’s my take on how to survive the summer without putting on a pound.
10 June 2024
Most people get – on a conceptual level at least – that they should probably eat a bit better than they do, they should probably move more and take the time for more self care in order to live a long and happy life. ‘Life’ seems to get in the way of achieving that. Many of us are juggling jobs and the complexities of modern relationships, leaving little time to dedicate to the business of ‘being healthy’. Convenience often wins. It’s not that that’s wrong per se, but here’s the thing: all the time we are not eating or moving or living as well as we know to do, we are silently getting sicker. That may actually be going-to-hospital sick or it may just mean having health niggles that bother us greatly but that we have learned to cope with. I’m talking here about things like IBS or other tummy troubles, PMT, arthritis, stress or anxiety, haywire hormones, or possibly weight that has crept on over the years and you can’t seem to shift it, no matter what you try. What I want to share with you today is that the food you eat matters more than you can possibly imagine. And that, in many cases, simply by making changes to your diet, the symptoms of some of these conditions can be improved so markedly that there is a really profound shift in how you experience life. 
by Megan Oliver 17 May 2024
I hear this often from both clients and friends alike. They start a new diet and it's their partners who lose weight, whilst theirs doesn't shift.
22 April 2024
The sun is out and it’s feeling more and more like spring but this brings problems for many of us hayfever sufferers. The number of us struggling with hayfever is rising and it can be hugely debilitating. Nutrition can play an important role as a preventative measure, as well as helping dampen down symptoms.  What is Histamine? Histamine is a chemical produced by mast cells in our body as part of our immune response. It can also occur in everyday foods such as cheese, wine and fermented foods, and some foods can encourage our body to produce more histamine.
by Marcus Elliott 12 January 2024
The truth is that calories can be misleading and by purely focusing on them can hamper your weight loss goals. Here’s why: Not all calories are created equal! Food is information for the body and each individual food will have a different effect on your metabolism. Calorie counting can be inaccurate. Food labels are based on averages and the way your food is prepared and the quality of the ingredients can affect the number of calories it contains. Calories do not take into account caloric availability. How your body breaks the food down is not the same as how they measure it in a lab.