Semaglutide GLP-1 medication and perimenopause

Semaglutide GLP-1 Medication and Perimenopause:

What You Need to Know

Why GLP-1 Medication Can Help

During perimenopause, many women notice changes in weight, appetite, and how their body manages energy. Shifts in oestrogen and progesterone can make it easier to gain fat—particularly around the middle—and harder to keep blood sugar balanced.

This is where GLP-1 medications (semaglutides) can be helpful. They work by:

● Slowing down digestion, which helps you feel full for longer.

● Supporting steadier blood sugar levels.

● Reducing appetite and cravings, making it easier to manage portion sizes.

In perimenopause, when hormones naturally make weight regulation more difficult, GLP-1s can offer extra support.

They are however controversial for good reason. We have discussed the pro’s and

con’s of Semaglutides in previous blogs, so refer back to make sure you are informed

of the potentially serious side effects.

How Nutrition Can Support You on Semaglutides

Medication works best when paired with nourishing food and lifestyle choices. Here are

some simple, supportive tips:

1. Prioritise protein

● Helps maintain muscle (important as muscle naturally declines in midlife).

● Keeps you fuller for longer.

● Supports hormone production.

2. Focus on fibre

● Supports digestion and gut health.

● Keeps blood sugar steadier.

● Fills you up with fewer calories.

3. Stay hydrated

● Semaglutides can sometimes reduce your thirst—so be mindful of fluids.

● Aim for regular sips of water or herbal teas across the day.

4. Smaller, balanced meals

● Because food moves more slowly through the gut on Semaglutides, large heavy

meals may feel uncomfortable.

● Choose smaller portions with a balance of protein, fibre, and healthy fats.

The Takeaway

Semaglutide medication can be a helpful tool during perimenopause, but it’s not a magic fix on its own. Pairing it with a balanced diet—rich in protein, fibre, and whole foods—helps you feel your best, supports long-term health, and makes the medication more effective.

Regaining the weight you lost when you come off Semaglutides is very common. My biggest tip is to use the time you are on them to really look at why you were gaining weight in the first place and create a sustainable way of eating to stop that weight coming back on.

If you are considering taking medication such as Ozempic, Mounjaro or Wegovy, or perhaps you are already on one, contact me to get nutritional support to minimise side effects and make sure that weight stays off for good!