Oestrogen 101: What You Really Need to Know
Oestrogen often gets a bad reputation, blamed for PMS, fibroids, or breast cancer. But the
truth? Oestrogen is essential for nearly every system in your body, from your bones and
heart to your brain, gut, and skin. Understanding it is key to managing hormonal
health—especially during perimenopause, menopause, or while on HRT.
The Different Types of Oestrogen
There isn’t just one:
● Estradiol (E2): Most potent, dominant before menopause.
● Estrone (E1): Weaker, produced in fat tissue, especially after menopause.
● Estriol (E3): Mild, important during pregnancy.
● Estetrol (E4): Produced by the fetal liver during pregnancy.
Each plays a role depending on life stage and hormonal needs.
Where Oestrogen Comes From
Premenopause: Mainly the ovaries, fluctuating with your cycle.
Postmenopause: Fat tissue, adrenal glands, and other tissues convert precursors
into weaker oestrogens. Even in small amounts, these help maintain balance.
Signs of Imbalance
High oestrogen: Breast tenderness, heavy periods, mood swings, bloating, weight on
hips/thighs.
Low oestrogen: Hot flushes, night sweats, brain fog, low libido, belly fat, bone loss, joint
pain.
Oestrogen Detox Matters
After oestrogen does its job, it must be safely eliminated. Poor detox can lead to:
● Build-up of harmful metabolites
● Hormonal imbalances and inflammation
● Symptoms like bloating, heavy periods, and weight gain
Supporting the liver, gut, and elimination pathways is key. Eat fibre, cruciferous veg, stay
hydrated, and nurture your microbiome.
Testing Can Help
Functional tests like the DUTCH test or stool analysis can reveal how well your body
processes and clears oestrogen, especially if you’re perimenopausal, menopausal, or on
HRT.
The Bottom Line
Oestrogen is vital, but balance is everything. Proper detox, gut support, and testing where
needed can help you maintain healthy levels, prevent unwanted symptoms, and support
overall wellbeing.
The Oxford Clinic for Nutrition
24 Barley Close, WallingfordUnited Kingdom











